About Düsseldorf Düsseldorf is the capital and second-largest city (after Cologne) of North Rhine-Westphalia federal state, with a population of 617,280 residents. Located on the banks of the Rhine River, Düsseldorf is a regional economic, financial and cultural center. The beautiful city impresses with elegance and style and has a wide range of activities to offer - from museums, art and culture to high-end shopping, sightseeing, going out and dining at numerous restaurants